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Aphios® Pharma LLC is dedicated to the discovery, development and commercialization of FDA-approved cannabis-based drugs for cancer and supportive care, central nervous system (CNS) disorders and other debilitating diseases. We will discover, manufacture and deliver pharmaceutical-grade natural cannabinoids in stable, bioavailable nanoformulations, following current good manufacturing practices (cGMP) of the FDA under Schedule 1 licenses from the Drug Enforcement Agency (DEA). These cannabinoid nanoformulations will be used to establish clinical evidence for treating highly unmet diseases such as cancer, cancer induced peripheral neuropathic pain (CIPNP), cachexia related to cancer and/or cancer therapy, and chemotherapy induced nausea and vomiting (CINV) as well as CNS disorders such as opioid addiction, epilepsy and multiple sclerosis that are only partially and anecdotally addressed by medical marijuana
Aleta Biotherapeutics is an immuno-oncology company focused on transforming cellular therapeutics to allow a broad spectrum of cancer indications to be targeted, including currently intractable solid tumors. Aleta Biotherapeutics is an immuno-oncology company focused on transforming cellular therapeutics to allow a broad spectrum of cancer indications to be targeted, including currently intractable solid tumors. We confront antigen loss and tumor heterogeneity by targeting multiple antigens simultaneously with a single CAR (CAR19) and license CAR19 cell expansion & persistence through normal B cell CD19-targeting